Genome Editing and Engineering: From TALENs, ZFNs and CRISPRs to

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Genome Editing and Engineering: From TALENs, ZFNs and CRISPRs to Specs
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BindingHardcover
Book TitleGenome Editing and Engineering: From TALENs, ZFNs and CRISPRs to
Number of Pages498 Pages
Publication NameGenome Editing and Engineering : from Talens, Zfns and Crisprs to Molecular Surgery
LanguageEnglish
PublisherCambridge University Press
Item Height1.2 in
Publication Year2018
SubjectLife Sciences / Genetics & Genomics, Chemistry / General
TypeTextbook
Item Weight42 Oz
Item Length9.9 in
AuthorKrishnarao Appasani
Subject AreaScience
Item Width7 in
FormatHardcover
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Recent advances in genome editing tools using endonucleases such as TALENs, ZFNs, and CRISPRs, combined with genomic engineering technologies, have opened up a wide range of opportunities from applications in the basic sciences and disease biology research, to the potential for clinical applications and the development of new diagnostic tools. This complete guide to endonuclease-based genomic engineering gives readers a thorough understanding of this rapidly expanding field. Chapters cover the discovery, basic science, and application of these techniques, focusing particularly on their potential relevance to the treatment of cancer, and cardiovascular and immunological disease. The final section discusses the legal and ethical issues which accompany the technology. Providing authoritative coverage of the potential that genome editing and engineering have, this is an ideal reference for researchers and graduate students and those working in the biotechnology and pharmaceutical industries, as well as in a clinical setting.